Driven by Care,
Powered by Innovation

Overview

MediWound Ltd. (Nasdaq: MDWD) is a global leader in next-generation enzymatic therapeutics for non-surgical tissue repair. Its solutions selectively remove non-viable hazardous tissue while preserving healthy tissue, offering a safer and more effective alternative to traditional methods. With robust in-house research, development, and manufacturing capabilities, the company produces and commercializes cutting-edge biologics for wound and burn care that exceed existing standards of care, improve patient outcomes, and reduce healthcare costs by eliminating the need for surgical interventions.

MediWound’s flagship product, NexoBrid®, is an FDA, EMA and PMDA approved orphan designated biologic, currently in use worldwide for treating severe burns. Building on its proprietary enzymatic technology, MediWound is advancing EscharEx®, a promising Phase III pipeline drug for the treatment of chronic wounds, including diabetic foot ulcers and venous leg ulcers.

Bench to Bedside

R&D | Manufacturing | Commercial

MediWound delivers fully vertically integrated solutions, powered by an exceptional R&D team with a track record of 14/14 successful clinical trials and over 150 peer-reviewed publications. The company operates a state-of-the-art cGMP-certified sterile manufacturing facility, ensuring the highest standards of quality and scalability to meet global demand. Through its global commercialization effort MediWound has successfully treated over 15,000 patients worldwide, solidifying its position as a leader in advanced wound care innovation.

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R&D

•  In Vitro / In Vivo Models:  Advanced efficacy and safety testing
•  Analytical Methods:  Precise characterization and quality control
•  Product Formulation:  Optimized for stability, ease of use, and therapeutic performance
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Manufacturing

•  cGMP Certified:  Compliant with global standards
•  Aseptic Processing:  Sterile, high-integrity production
•  Development Suites:  Advanced formulation and scale-up
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Commercialization

•  U.S.:  Strategic partnership with Vericel Corp
•  Europe:  Direct sales; PMI promotion in DACH region
•  Global:  Collaborations in Japan, India, Australia, and additional markets

Product Pipeline

Novel Therapies for a Better Standard of Care
Product / Indication
Development
Phase 1
Phase 2
Phase 3
Registration
Commercialized
NexoBrid®
Adult burn eschar removal Approved
Pediatric burn eschar removal Approved
Battlefield burn eschar removal DoD funded
Blast injury treatment
VLU debridement
DFU debridement EIC supported
Post traumatic wound debridement

Leadership

Board of Directors